Codon Usage in S. cerevisiae

Figure 1 displays the relative frequencies of each of the 64 codons.

There is a 25-fold difference in abundance between the most and least abundant amino-encoding codons. GAA, encoding glutamate, occurs most frequently, comprising 4.6% of the 2,851,170 codons in the sequences. CGG is the least abundant, comprising only .18% of the codons.

Rank	Symbol	Count	Expected	Frequency	Expected	ZScore	Ratio
			Count				Frequency
_____________________________________________________________________________________

1	TAA	2939	65615.99	1.00E-03	2.30E-02	247.55	0.04
2	TAG	1398	42314.34	4.90E-04	1.48E-02	200.40	0.03
3	TGA	1824	26660.11	6.40E-04	9.30E-03	152.82	0.07
4	GTA	34474	67204.05	1.20E-02	2.35E-02	127.77	0.51
5	ATA	52516	78931.36	1.84E-02	2.76E-02	95.35	0.67
6	GCG	17837	33866.06	6.20E-03	1.18E-02	87.62	0.53
7	ACG	23368	39775.79	8.10E-03	1.39E-02	82.85	0.59
8	CGA	8768	19069.43	3.00E-03	6.60E-03	74.85	0.46
9	TAT	54136	73148.25	1.89E-02	2.56E-02	71.22	0.74
10	CGG	5223	12297.47	1.80E-03	4.30E-03	63.93	0.42
11	GTG	31209	43338.45	1.09E-02	1.52E-02	58.71	0.72
12	CAT	39073	52321.43	1.37E-02	1.83E-02	58.46	0.75
13	GTC	32133	43977.96	1.12E-02	1.54E-02	56.92	0.73
14	CTC	15965	24773.12	5.50E-03	8.60E-03	56.21	0.64
15	CAC	21858	30713.20	7.60E-03	1.07E-02	50.80	0.71
16	GTT	61896	74918.61	2.17E-02	2.62E-02	48.22	0.83
17	ACT	56543	68759.89	1.98E-02	2.41E-02	47.16	0.82
18	ACA	50790	61679.51	1.78E-02	2.16E-02	44.33	0.82
19	CGC	7583	12478.93	2.60E-03	4.30E-03	43.92	0.61
20	TGT	23251	29720.51	8.10E-03	1.04E-02	37.72	0.78
21	CTT	35796	42202.21	1.25E-02	1.48E-02	31.42	0.85
22	GGG	17607	21830.82	6.10E-03	7.60E-03	28.70	0.81
23	CCG	15145	19077.01	5.30E-03	6.60E-03	28.56	0.79
24	GCA	46371	52515.41	1.62E-02	1.84E-02	27.06	0.88
25	ACC	35059	40362.74	1.22E-02	1.41E-02	26.59	0.87
26	TGC	14083	17446.23	4.90E-03	6.10E-03	25.54	0.81
27	CGT	17851	21258.47	6.20E-03	7.40E-03	23.46	0.84
28	AAT	103160	109090.84	3.61E-02	3.82E-02	18.31	0.95
29	ATC	48203	51652.26	1.69E-02	1.81E-02	15.32	0.93
30	AGT	41330	44324.17	1.44E-02	1.55E-02	14.33	0.93
31	GGA	31934	33852.61	1.12E-02	1.18E-02	10.49	0.94
32	TCG	25049	26670.71	8.70E-03	9.30E-03	9.98	0.94
33	TAC	41031	42938.75	1.43E-02	1.50E-02	9.28	0.96
34	ATT	86264	87992.14	3.02E-02	3.08E-02	5.92	0.98
35	GCT	57340	58543.81	2.01E-02	2.05E-02	5.03	0.98
36	CCC	19678	19358.51	6.90E-03	6.70E-03	-2.30	1.02
37	GCC	34942	34365.80	1.22E-02	1.20E-02	-3.13	1.02
38	CTA	38741	37856.54	1.35E-02	1.32E-02	-4.58	1.02
39	GAG	55574	53730.11	1.94E-02	1.88E-02	-8.03	1.03
40	AGG	27215	25640.37	9.50E-03	8.90E-03	-9.88	1.06
41	GAC	56979	54522.97	1.99E-02	1.91E-02	-10.62	1.05
42	AGC	28516	26018.73	1.00E-02	9.10E-03	-15.55	1.10
43	AAC	69594	64037.40	2.44E-02	2.24E-02	-22.21	1.09
44	CAG	34942	30266.58	1.22E-02	1.06E-02	-27.02	1.15
45	CCT	38116	32978.17	1.33E-02	1.15E-02	-28.46	1.16
46	ATG	59397	50901.15	2.08E-02	1.78E-02	-38.00	1.17
47	GGC	27975	22152.96	9.80E-03	7.70E-03	-39.27	1.26
48	CTG	30585	24412.87	1.07E-02	8.50E-03	-39.67	1.25
49	GAT	108025	92882.54	3.78E-02	3.25E-02	-50.52	1.16
50	TCA	54204	41357.72	1.90E-02	1.45E-02	-63.63	1.31
51	TTT	76607	59001.02	2.68E-02	2.06E-02	-73.24	1.30
52	AAA	120849	97857.47	4.23E-02	3.43E-02	-74.79	1.23
53	TCC	40355	27064.27	1.41E-02	9.40E-03	-81.17	1.49
54	AAG	87151	63106.19	3.05E-02	2.21E-02	-96.79	1.38
55	TTC	52544	34634.18	1.84E-02	1.21E-02	-96.83	1.52
56	TGG	29866	17192.54	1.04E-02	6.00E-03	-96.95	1.74
57	TCT	67117	46105.30	2.35E-02	1.61E-02	-98.66	1.46
58	TTA	75537	52925.54	2.64E-02	1.85E-02	-99.21	1.43
59	AGA	59935	39760.00	2.10E-02	1.39E-02	-101.89	1.51
60	CCA	50149	29582.32	1.75E-02	1.03E-02	-120.20	1.70
61	CAA	76107	46933.76	2.66E-02	1.64E-02	-135.78	1.62
62	GGT	64481	37738.65	2.26E-02	1.32E-02	-138.58	1.71
63	GAA	129982	83318.19	4.55E-02	2.92E-02	-164.08	1.56
64	TTG	76985	34130.54	2.70E-02	1.19E-02	-233.37	2.26